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New add-on therapy to infliximab for ulcerative colitis Research study

A clinical trial to assess the effectiveness of a new add-on therapy (PF-06687234) to infliximab.

ANAVEX®2-73 for mild cognitive impairment or early Alzheimer’s disease Research study

 A clinical trial that aims to assess the safety and efficacy of a new drug (ANAVEX®2-73) for the treatment of early Alzheimer’s disease.

Comparing liver cancer medications in treating hepatocellular carcinoma Research study

A clinical trial comparing different liver cancer medications (sorafenib, cabozantinib or a combination of cabozantanib and atezolizumab) for treating liver cancer (hepatocellular carcinoma).

Seladelpar as a treatment for primary biliary cholangitis (PBC) Research study

A study to evaluate the safety and effectiveness of an investigational drug, seladelpar, in treating patients with primary biliary cholangitis (PBC).

Tirzepatide for people with type 2 diabetes Research study

A clinical trial investigating the safety and effectiveness of tirzepatide taken once weekly compared to insulin taken once daily in people with type 2 diabetes and increased cardiovascular risk.

Vagus nerve stimulation (VNS) device for the treatment of epilepsy Research study

This post-market study involves collecting information for an already approved VNS device to get detailed information about the outcomes of people receiving the approved treatment.

Filgotinib for moderately to severely active Crohn’s disease Research study

This trial aimed to evaluate the efficacy and safety of Filgotinib in the induction and maintenance of remission in people with moderately to severely active Crohn’s disease.

Remibrutinib for chronic spontaneous urticaria Research study

A clinical trial to assess a new drug for chronic spontaneous urticaria (CSU) not controlled with antihistamine medication or omalizumab (Xolair®) in the past.

Amlitelimab (KY1005) for moderate to severe atopic dermatitis Research study

A clinical trial to assess a new drug called amlitelimab (KY1005) as a treatment for moderate to severe atopic dermatitis (eczema)

WVE-003 in patients with Huntington’s disease Research study

A multicentre, randomised, double-blind, placebo-controlled, phase 1b/2a study of WVE-003 in patients with Huntington’s disease.

BI 456906 for non-alcoholic steatohepatitis (NASH) and liver fibrosis Research study

A study to test whether different doses of BI 456906 are effective in people with a liver disease called non-alcoholic steatohepatitis (NASH) and liver fibrosis.

Mirikizumab for moderate to severely active Crohn’s disease Research study

A clinical trial to assess the safety and effectiveness of a new drug, mirikizumab, for moderate to severely active Crohn’s disease.

Atezolizumab plus bevacizumab for treated hepatocellular patients at high risk of recurrence Research study

A clinical trial to assess the effectiveness of a combination immunotherapy versus active surveillance for treated hepatocellular patients who are at high risk of recurrence.

New blood test to detect bowel cancer Research study

Seeking adults diagnosed with bowel cancer who will be having surgery, chemotherapy or radiation therapy in the next 30 days for a study to assess the effectiveness of a new blood test to detect bowel cancer.

New potential treatment for adult males with Tourette Syndrome Research study

A study to evaluate the safety and efficacy of new drug in male patients aged 18 to 50 with Tourette Syndrome (TS).

New blood test to diagnose and monitor autoimmune blistering skin conditions Research study

A prospective study on serum antibodies against target antigens of bullous autoimmune diseases and genetic susceptibility.

Effects of denosumab on normal breast tissue for BRCA gene carriers Research study

A trial to investigate the effects of denosumab on normal breast tissue in patients with BRCA 1 or 2 mutations and to determine if the drug has the potential to prevent breast cancer.

mRNA vaccine for preventing cytomegalovirus infection Research study

A clinical trial seeking to develop an mRNA vaccine for preventing cytomegalovirus (CMV) infection.

Understanding antigen triggers in psoriasis Research study

A non-interventional study to investigate triggers in psoriasis.

A new insulin when used in combination with oral medications to manage type 2 diabetes Research study

A clinical trial to investigate the safety and effectiveness of a new insulin (INS068) when used in combination with oral medications to manage type 2 diabetes.