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Deferiprone as a treatment for Alzheimer’s disease Research study

A clinical trial to investigate whether deferiprone delays dementia progression in the early stages of dementia.

Antipsychotic dose reduction to improve recovery and function in young people with psychosis Research study

The REDUCE study is testing whether reducing the dosage of antipsychotic medication of people recovering from their first episode of psychosis can lead to them having better recovery outcomes.

Perampanel to control and prevent seizures in patients with brain tumours Research study

A randomised controlled trial assessing the safety and effectiveness of perampanel, an anti-epileptic drug, in people with brain tumours.

Etrolizumab for people with ulcerative colitis who have never used TNF inhibitors Research study

This study aimed to evaluate etrolizumab as a treatment for patients with moderate to severe ulcerative colitis who are naive to TNF inhibitors.

KPL-716 to reduce pruritus in people with prurigo nodularis Research study

A clinical trial to assess a new drug (KPL-716) for prurigo nodularis (PN).

PRAX-944 as a potential treatment for essential tremor Research study

A clinical trial evaluating the efficacy, safety, tolerability, and pharmacokinetics of PRAX-944 in adults with essential tremor.

Donanemab in early symptomatic Alzheimer’s disease Research study

A study to determine the safety and efficacy of a drug called donanemab in treating or delaying the progression of Alzheimer’s dementia.

Benralizumab for moderate to severe atopic dermatitis Research study

A clinical trial to assess the safety and effectiveness of a new drug called benralizumab for atopic dermatitis (eczema).

New drug for moderate to severe hidradenitis suppurativa Research study

A clinical trial to assess the safety and effectiveness of a new drug for hidradenitis suppurativa.

Spesolimab for the treatment of hidradenitis suppurativa Research study

A study to measure how safe and effective spesolimab (the study drug) is in treating participants with moderate to severe hidradenitis suppurativa (HS).

Spesolimab for the treatment of generalised pustular psoriasis Research study

A study to test whether spesolimab prevents flare-ups in patients with generalised pustular psoriasis.

Efgartigimod for the treatment of pemphigus vulgaris or pemphigus foliaceous Research study

A clinical trial to assess how safe and effective the study drug. efgartigimod, is in treating participants with pemphigus who are also receiving oral corticosteroids.

Bimekizumab for the treatment of moderate to severe hidradenitis suppurativa Research study

In this study, we tested whether bimekizumab helps people with a skin disease called hidradenitis suppurativa.

Nemolizumab for the treatment of moderate to severe atopic dermatitis Research study

A clinical trial to assess safety and effectiveness of a new drug for eczema called nemolizumab.

HREC meeting dates and deadlines

The Office for Research has monthly deadlines for submission of new research project applications for review by the RMH Human Research Ethics Committee (HREC).

Ligelizumab for chronic spontaneous urticaria Research study

A clinical trial to assess a new drug called ligelizumab for the treatment of chronic spontaneous urticaria (CSU).

Extended temozolomide chemotherapy period for glioblastoma Research study

A clinical trial to determine if extending temozolomide treatment (chemotherapy) after radiation improves survival in patients with newly diagnosed glioblastoma.

Novel blood collection device to help resource-poor countries with diagnostic testing Research study

Seeking VIDS patients who are living with hepatitis B, hepatitis C or HIV to provide blood samples for the development of a new diagnostic test sampling and storage device for resource-poor countries.

Mirikizumabin for moderately to severely active ulcerative colitis Research study

A clinical trial to assess the safety and effectiveness of a new drug, mirikizumab, in conventional-failed and biologic-failed patients with moderately to severely active ulcerative colitis (UC).

Treatment for moderately to severely active ulcerative colitis Research study

A clinical trial to assess whether guselkumab and golimumab when used together is safe and effective for treating participants with moderately to severely active ulcerative colitis (UC).