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Bimekizumab for the treatment of moderate to severe hidradenitis suppurativa Research study

In this study, we tested whether bimekizumab helps people with a skin disease called hidradenitis suppurativa.

Nemolizumab for the treatment of moderate to severe atopic dermatitis Research study

A clinical trial to assess safety and effectiveness of a new drug for eczema called nemolizumab.

HREC meeting dates and deadlines

The Office for Research has monthly deadlines for submission of new research project applications for review by the RMH Human Research Ethics Committee (HREC).

Ligelizumab for chronic spontaneous urticaria Research study

A clinical trial to assess a new drug called ligelizumab for the treatment of chronic spontaneous urticaria (CSU).

Extended temozolomide chemotherapy period for glioblastoma Research study

A clinical trial to determine if extending temozolomide treatment (chemotherapy) after radiation improves survival in patients with newly diagnosed glioblastoma.

Novel blood collection device to help resource-poor countries with diagnostic testing Research study

Seeking VIDS patients who are living with hepatitis B, hepatitis C or HIV to provide blood samples for the development of a new diagnostic test sampling and storage device for resource-poor countries.

Mirikizumabin for moderately to severely active ulcerative colitis Research study

A clinical trial to assess the safety and effectiveness of a new drug, mirikizumab, in conventional-failed and biologic-failed patients with moderately to severely active ulcerative colitis (UC).

Treatment for moderately to severely active ulcerative colitis Research study

A clinical trial to assess whether guselkumab and golimumab when used together is safe and effective for treating participants with moderately to severely active ulcerative colitis (UC).

New add-on therapy to infliximab for ulcerative colitis Research study

A clinical trial to assess the effectiveness of a new add-on therapy (PF-06687234) to infliximab.

ANAVEX®2-73 for mild cognitive impairment or early Alzheimer’s disease Research study

 A clinical trial that aims to assess the safety and efficacy of a new drug (ANAVEX®2-73) for the treatment of early Alzheimer’s disease.

Comparing liver cancer medications in treating hepatocellular carcinoma Research study

A clinical trial comparing different liver cancer medications (sorafenib, cabozantinib or a combination of cabozantanib and atezolizumab) for treating liver cancer (hepatocellular carcinoma).

Seladelpar as a treatment for primary biliary cholangitis (PBC) Research study

A study to evaluate the safety and effectiveness of an investigational drug, seladelpar, in treating patients with primary biliary cholangitis (PBC).

Tirzepatide for people with type 2 diabetes Research study

A clinical trial investigating the safety and effectiveness of tirzepatide taken once weekly compared to insulin taken once daily in people with type 2 diabetes and increased cardiovascular risk.

Vagus nerve stimulation (VNS) device for the treatment of epilepsy Research study

This post-market study involves collecting information for an already approved VNS device to get detailed information about the outcomes of people receiving the approved treatment.

Filgotinib for moderately to severely active Crohn’s disease Research study

This trial aimed to evaluate the efficacy and safety of Filgotinib in the induction and maintenance of remission in people with moderately to severely active Crohn’s disease.

Remibrutinib for chronic spontaneous urticaria Research study

A clinical trial to assess a new drug for chronic spontaneous urticaria (CSU) not controlled with antihistamine medication or omalizumab (Xolair®) in the past.

Amlitelimab (KY1005) for moderate to severe atopic dermatitis Research study

A clinical trial to assess a new drug called amlitelimab (KY1005) as a treatment for moderate to severe atopic dermatitis (eczema)

WVE-003 in patients with Huntington’s disease Research study

A multicentre, randomised, double-blind, placebo-controlled, phase 1b/2a study of WVE-003 in patients with Huntington’s disease.

BI 456906 for non-alcoholic steatohepatitis (NASH) and liver fibrosis Research study

A study to test whether different doses of BI 456906 are effective in people with a liver disease called non-alcoholic steatohepatitis (NASH) and liver fibrosis.

Mirikizumab for moderate to severely active Crohn’s disease Research study

A clinical trial to assess the safety and effectiveness of a new drug, mirikizumab, for moderate to severely active Crohn’s disease.