Clinical trials are a very important part of the research process. New treatments, medications and medical devices cannot be approved for use in Australia without going through clinical trials. Find out more about clinical trials.
Metformin and atorvastatin for adults with depression
The Hearts and Minds clinical trial is aiming to determine whether metformin or atorvastatin help to reduce symptoms of major depression and improve quality of life.
A new insulin when used in combination with oral medications to manage type 2 diabetes
A clinical trial to investigate the safety and effectiveness of a new insulin (INS068) when used in combination with oral medications to manage type 2 diabetes.
A new potential therapy for depression
This large international trial will examine the efficacy and safety of a new potential therapy for treatment-resistant depression.
Preserving pancreas function can make glucose control easier and reduce the need to use injected insulin
ACeD-it! Seeking participants for a new coeliac disease study
Improving tolerance to gluten in people living with coeliac disease may enhance their quality of life
Amlitelimab (KY1005) for moderate to severe atopic dermatitis
A clinical trial to assess a new drug called amlitelimab (KY1005) as a treatment for moderate to severe atopic dermatitis (eczema)
ANAVEX®2-73 for mild cognitive impairment or early Alzheimer’s disease
A clinical trial that aims to assess the safety and efficacy of a new drug (ANAVEX®2-73) for the treatment of early Alzheimer’s disease.
Antipsychotic dose reduction to improve recovery and function in young people with psychosis
The REDUCE study is testing whether reducing the dosage of antipsychotic medication of people recovering from their first episode of psychosis can lead to them having better recovery outcomes.
Assessing a new tablet for plaque psoriasis
Understanding the effect of medication on the body's inflammatory response may lead to new treatments for autoimmune conditions, including psoriasis.
Atezolizumab plus bevacizumab for treated hepatocellular patients at high risk of recurrence
A clinical trial to assess the effectiveness of a combination immunotherapy versus active surveillance for treated hepatocellular patients who are at high risk of recurrence.
The research study is testing an investigational product called TAVO101 designed specifically for people diagnosed with moderate to severe atopic dermatitis (eczema),
Barzolvolimab in patients with Chronic Spontaneous Urticaria
This clinical trial seeks to assess the safety and effectiveness of Barzolvolimab in participants with Chronic Spontaneous Urticaria (CSU) who remain symptomatic despite use of antihistamine treatment.
Benralizumab for moderate to severe atopic dermatitis
A clinical trial to assess the safety and effectiveness of a new drug called benralizumab for atopic dermatitis (eczema).
Benralizumab for the treatment of bullous pemphigoid
A research project to measure how safe and effective benralizumab is in treating participants with bullous pemphigoid (BP).
BI 456906 for non-alcoholic steatohepatitis (NASH) and liver fibrosis
A study to test whether different doses of BI 456906 are effective in people with a liver disease called non-alcoholic steatohepatitis (NASH) and liver fibrosis.
Bimekizumab for the treatment of moderate to severe hidradenitis suppurativa
In this study, we tested whether bimekizumab helps people with a skin disease called hidradenitis suppurativa.
Bitopertin as a treatment for erythropoietic protoporphyria
Research project to measure how safe and effective bitopertin (DISC-1459) is in treating participants with erythropoietic protoporphyria.
Can fenofibrate protect against eye damage in early retinopathy for adults with Type 1 diabetes
A clinical trial to assess whether fenofibrate can protect against eye damage in early retinopathy in adults with type 1 diabetes
Can over-the-counter supplements reduce diabetes-related painful peripheral neuropathy?
The Mito-PPND Study seeks to assess the safety and effectiveness of a combination of over-the-counter supplements for reducing painful peripheral neuropathy
Cannabidiol (CBD) as a potential new treatment for mental ill-health in youths
The Cannabidiol for At Risk Youth (CanARY) study is testing a potential new treatment called cannabidiol (CBD) for helping people with symptoms that might indicate risk of a psychotic disorder. CBD is a non-psychoactive treatment, meaning it does not give you a ‘high’.
Combination treatment for locally advanced or metastatic ER-positive breast cancer
A phase II, multicentre, randomised study to compare the efficacy of venetoclax plus fulvestrant as a combination treatment for locally advanced or metastatic ER-positive breast cancer.
Comparing liver cancer medications in treating hepatocellular carcinoma
A clinical trial comparing different liver cancer medications (sorafenib, cabozantinib or a combination of cabozantanib and atezolizumab) for treating liver cancer (hepatocellular carcinoma).
Deferiprone as a treatment for Alzheimer’s disease
A clinical trial to investigate whether deferiprone delays dementia progression in the early stages of dementia.
Denosumab as a prevention for breast cancer in women with a BRCA1 mutation
This research is to find out whether the study medication, denosumab, can help prevent breast cancer in women with a BRCA1 mutation.
Donanemab in early symptomatic Alzheimer’s disease
A study to determine the safety and efficacy of a drug called donanemab in treating or delaying the progression of Alzheimer’s dementia.
Effects of denosumab on normal breast tissue for BRCA gene carriers
A trial to investigate the effects of denosumab on normal breast tissue in patients with BRCA 1 or 2 mutations and to determine if the drug has the potential to prevent breast cancer.
Efgartigimod for the treatment of pemphigus vulgaris or pemphigus foliaceous
A clinical trial to assess how safe and effective the study drug. efgartigimod, is in treating participants with pemphigus who are also receiving oral corticosteroids.
Etrasimod for the treatment of ulcerative colitis
A clinical trial to assess the safety and efficacy of an oral medication called Etrasimod for moderately active ulcerative colitis (UC).
Etrolizumab for people with ulcerative colitis who have never used TNF inhibitors
This study aimed to evaluate etrolizumab as a treatment for patients with moderate to severe ulcerative colitis who are naive to TNF inhibitors.
Experimental treatment for Parkinson’s disease
This is a study of an experimental treatment (referred to as “study drug”) called CVL-751 as a possible treatment for Parkinson’s disease.