Our medical, nursing and allied health clinicians are increasingly involved in research to improve the care of our patients. This is reflected in the breadth of our research publications.
Determining the cost of first-ever seizures: A narrative review and future directions
Foster, E; Ademi, Z; Lawn, N; Chen, ZB; Carney, P; Liew, D; O'Brien, TJ; Kwan, P
(2019), EPILEPSY & BEHAVIOR, 291-294
Antiepileptic drugs and foetal malformation: analysis of 20 years of data in a pregnancy register
Vajda, FJE; Graham, JE; Hitchcock, AA; Lander, CM; O'Brien, TJ; Eadie, MJ
(2019), SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 6-11
Disease-modifying effects of a novel T-type calcium channel antagonist, Z944, in a model of temporal lobe epilepsy
Casillas-Espinosa, PM; Shultz, SR; Braine, EL; Jones, NC; Snutch, TP; Powell, KL; O'Brien, TJ
(2019), PROGRESS IN NEUROBIOLOGY
Role of cerebral glutamate in post-stroke epileptogenesis
Nicolo, JP; O'Brien, TJ; Kwan, P
(2019), NEUROIMAGE-CLINICAL
Deep brain stimulation for Parkinson's disease modulates high-frequency evoked and spontaneous neural activity
Sinclair, NC; McDermott, HJ; Fallon, JB; Perera, T; Brown, P; Bulluss, KJ; Thevathasan, W
(2019), NEUROBIOLOGY OF DISEASE
The epilepsy bioinformatics study for anti-epileptogenic therapy (EpiBioS4Rx) clinical biomarker: Study design and protocol
Vespa, PM; Shrestha, V; Abend, N; Agoston, D; Au, A; Bell, MJ; Bleck, TP; Blanco, MB; Claassen, J; Diaz-Arrastia, R; Duncan, D; Ellingson, B; Foreman, B; Gilmore, EJ; Hirsch, L; Hunn, M; Kamnaksh, A; McArthur, D; Morokoff, A; O'Brien, T; O'Phelan, K; Robertson, CL; Rosenthal, E; Staba, R; Toga, A; Willyerd, FA; Zimmermann, L; Yam, E; Martinez, S; Real, C; Engel, J; Denes, A; Alicia, A; Michael, JB; Thomas, PB; Craig, B; Manuel, BB; Ross, B; Brian, TB; Jan, C; Robert, C; James, C; Lisa, C; Karen, C; Ramon, DA; Dominique, D; Benjamin, E; Jerome, E; Brandon, F; Aristea, G; Emily, G; Olli, G; Neil, H; Jed, H; Hirsch, L; Martin, H; Nathalie, J; Leigh, J; Nigel, J; Andres, K; David, M; Martin, M; Andrew, M; Solomon, M; Wenzhue, M; Terence, O; Kristine, O; Asla, P; Rema, R; Courtney, R; Eric, R; Sandy, S; Terrance, S; Richard, S; Arthur, T; Jack, V; Paul, V; Frederick, W; Lara, Z
(2019), NEUROBIOLOGY OF DISEASE, 110-114
What is the therapeutic mechanism of pedunculopontine nucleus stimulation in Parkinson's disease?
Thevathasan, W; Moro, E
(2019), NEUROBIOLOGY OF DISEASE, 67-74
Electrophysiological biomarkers of epileptogenicity after traumatic brain injury
Perucca, P; Smith, G; Santana-Gomez, C; Bragin, A; Staba, R
(2019), NEUROBIOLOGY OF DISEASE, 69-74
Incidence of pregnancy and disease-modifying therapy exposure trends in women with multiple sclerosis: A contemporary cohort study
Nguyen, AL; Havrdova, EK; Horakova, D; Izquierdo, G; Kalincik, T; van der Walt, A; Terzi, M; Alroughani, R; Duquette, P; Girard, M; Prat, A; Boz, C; Sola, P; Ferrara, D; Lugaresi, A; Lechner-Scott, J; Barnett, M; Grand'Maison, F; Grammond, P; Ramo-Tello, C; Turkoglu, R; McCombe, P; Pucci, E; Trojano, M; Granella, F; Spitaleri, D; Van Pesch, V; Soysal, A; Oreja-Guevara, C; Verheul, F; Vucic, S; Hodgkinson, S; Slee, M; Ampapa, R; Prevost, J; Menoyo, JLS; Skibina, O; Solaro, C; Olascoaga, J; Shaw, C; Madsen, KG; Naidoo, K; Hyde, R; Butzkueven, H; Jokubaitis, V
(2019), MULTIPLE SCLEROSIS AND RELATED DISORDERS, 235-243
Glioneuronal brainstem tumor - It's all in the eyes
Foster, E; McLean, C; White, O
(2019), JOURNAL OF CLINICAL NEUROSCIENCE, 151-153
Validation of a precision tremor measurement system for multiple sclerosis
Perera, T; Lee, WL; Yohanandan, SAC; Nguyen, AL; Cruse, B; Boonstra, FMC; Noffs, G; Vogel, AP; Kolbe, SC; Butzkueven, H; Evans, A; van der Walt, A
(2019), JOURNAL OF NEUROSCIENCE METHODS, 377-384
Using high-resolution Twin-Ion Metabolite Extraction (HiTIME) mass spectrometry with stable isotope labelling to investigate the metabolism of valproic acid in vivo
Leeming, MG; Cranswick, N; Wright, CE; Ziogas, J; O'Brien, TJ; Donald, WA; O'Hair, RAJ
(2019), INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
Targeting high-mobility group box protein 1 (HMGB1) in pediatric traumatic brain injury: Chronic neuroinflammatory, behavioral, and epileptogenic consequences
Webster, KM; Shultz, SR; Ozturk, E; Dill, LK; Sun, M; Casillas-Espinosa, P; Jones, NC; Crack, PJ; O'Brien, TJ; Semple, BD
(2019), EXPERIMENTAL NEUROLOGY
Determinants of social behavior deficits and recovery after pediatric traumatic brain injury
Zamani, A; Mychasiuk, R; Semple, BD
(2019), EXPERIMENTAL NEUROLOGY, 34-45
Distinct psychopathology profiles in patients with epileptic seizures compared to non-epileptic psychogenic seizures
Wang, AD; Leong, M; Johnstone, B; Rayner, G; Kalincik, T; Roos, I; Kwan, P; O'Brien, TJ; Velakoulis, D; Malpas, CB
(2019), EPILEPSY RESEARCH
Harmonization of the pipeline for seizure detection to phenotype post-traumatic epilepsy in a preclinical multicenter study on post-traumatic epileptogenesis
Casillas-Espinosa, PM; Andrade, P; Santana-Gomez, C; Paananen, T; Smith, G; Ali, I; Ciszek, R; Ndode-Ekane, XE; Brady, RD; Tohka, J; Hudson, MR; Perucca, P; Braine, EL; Immonen, R; Puhakka, N; Shultz, SR; Jones, NC; Staba, RJ; Pitkanen, A; O'Brien, TJ
(2019), EPILEPSY RESEARCH
Harmonization of lateral fluid-percussion injury model production and post-injury monitoring in a preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis
Ndode-Ekane, XE; Santana-Gomez, C; Casillas-Espinosa, PM; Ali, I; Brady, RD; Smith, G; Andrade, P; Immonen, R; Puhakka, N; Hudson, MR; Braine, EL; Shultz, SR; Staba, RJ; O'Brien, TJ; Pitkanen, A
(2019), EPILEPSY RESEARCH, 7-16
Informatics tools to assess the success of procedural harmonization in preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis
Ciszek, R; Ndode-Ekane, XE; Gomez, CS; Casillas-Espinosa, PM; Ali, I; Smith, G; Puhakka, N; Lapinlampi, N; Andrade, P; Kamnaksh, A; Immonen, R; Paananen, T; Hudson, MR; Brady, RD; Shultz, SR; O'Brien, TJ; Staba, RJ; Tohka, J; Pitkanen, A
(2019), EPILEPSY RESEARCH, 17-26
Infections after a traumatic brain injury: The complex interplay between the immune and neurological systems
Sharma, R; Shultz, SR; Robinson, MJ; Belli, A; Hibbs, ML; O'Brien, TJ; Semple, BD
(2019), BRAIN BEHAVIOR AND IMMUNITY, 63-74
Relative Seizure Relapse Risks Associated with Antiepileptic Drug Withdrawal After Different Seizure-Free Periods in Adults with Focal Epilepsy: A Prospective, Controlled Follow-Up Study
Wang, XS; He, RQ; Zheng, RY; Ding, SQ; Wang, Y; Li, XY; Hua, YJ; Zeng, QY; Xia, NG; Zhu, ZG; Kwan, P; Xu, HQ
(2019), CNS DRUGS, 1121-1132
Imaging After Thrombolysis and Thrombectomy: Rationale, Modalities and Management Implications
Ng, FC; Campbell, BCV
(2019), CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
Comparison of recent pivotal recommendations for the diagnosis and treatment of late-onset Pompe disease using diagnostic nodes-the Pompe disease burden scale
Hundsberger, T; Schoser, B; Leupold, D; Rosler, KM; Putora, PM
(2019), JOURNAL OF NEUROLOGY, 2010-2017
Treatment escalation leads to fewer relapses compared with switching to another moderately effective therapy
Chalmer, TA; Kalincik, T; Laursen, B; Sorensen, PS; Magyari, M; Sellebjerg, F; Magyari, M; Blinkenberg, M; Oturai, A; Frederiksen, JL; Heick, A; Jensen, MB; Stohr, L; Gora, M; Nielsen, HH; Illes, Z; Kant, M; Stenager, E; Pedersen, AT; Jensen, HB; Petersen, T; Rasmussen, PV; Rosendahl, L; Torring, J; Pfleger, CC; Weglewski, A
(2019), JOURNAL OF NEUROLOGY, 306-315
Scales to assess impulsive and compulsive behaviors in Parkinson's disease: Critique and recommendations
Evans, AH; Okai, D; Weintraub, D; Lim, SY; O'Sullivan, SS; Voon, V; Krack, P; Sampaio, C; Post, B; Leentjens, AFG; Martinez-Martin, P; Stebbins, GT; Goetz, CG; Schrag, A; Bhidayasiri, R; Brown, RG; Marinus, J; Mestre, TA; Violante, MR; Skorvanek, M
(2019), MOVEMENT DISORDERS, 791-798
DOI: 10.1002/mds.27689
De novo GRIN variants in NMDA receptor M2 channel pore-forming loop are associated with neurological diseases
Li, J; Zhang, J; Tang, WT; Mizu, RK; Kusumoto, H; XiangWei, WS; Xu, YC; Chen, WJ; Amin, JB; Hu, C; Kannan, V; Keller, SR; Wilcox, WR; Lemke, JR; Myers, SJ; Swanger, SA; Wollmuth, LP; Petrovski, S; Traynelis, SF; Yuan, HJ
(2019), HUMAN MUTATION, 2393-2413
DOI: 10.1002/humu.23895
Identifying the trajectory of social milestones 15-20 years after epilepsy surgery: Realistic timelines for postsurgical expectations
Coleman, H; McIntosh, A; Wilson, SJ
(2019), EPILEPSIA OPEN, 369-381
DOI: 10.1002/epi4.12341
The utility of an automated and ambulatory device for detecting and differentiating epileptic and psychogenic non-epileptic seizures
Naganur, VD; Kusmakar, S; Chen, ZB; Palaniswami, MS; Kwan, P; O'Brien, TJ
(2019), EPILEPSIA OPEN, 309-317
DOI: 10.1002/epi4.12327
Age-dependent release of high-mobility group box protein-1 and cellular neuroinflammation after traumatic brain injury in mice
Webster, KM; Sun, M; Crack, PJ; O'Brien, TJ; Shultz, SR; Semple, BD
(2019), JOURNAL OF COMPARATIVE NEUROLOGY, 1102-1117
DOI: 10.1002/cne.24589
The blood pressure paradox in acute ischemic stroke
Hong, L; Cheng, X; Lin, LT; Bivard, A; Ling, YF; Butcher, K; Dong, Q; Parsons, M; Spratt, N; Levi, C; Choi, PMC; Kleining, T; O'Brien, B; Lou, M
(2019), ANNALS OF NEUROLOGY, 331-339
DOI: 10.1002/ana.25428
Metabolic patterns and seizure outcomes following anterior temporal lobectomy
Cahill, V; Sinclair, B; Malpas, CB; McIntosh, AM; Chen, ZB; Vivash, LE; O'Shea, MF; Wilson, SJ; Desmond, PM; Berlangieri, SU; Hicks, RJ; Rowe, CC; Morokoff, AP; King, JA; Fabinyi, GC; Kaye, AH; Kwan, P; Berkovic, SF; O'Brien, TJ
(2019), ANNALS OF NEUROLOGY, 241-250
DOI: 10.1002/ana.25405