Our medical, nursing and allied health clinicians are increasingly involved in research to improve the care of our patients. This is reflected in the breadth of our research publications.
Protocol for a multicentre, parallel-group, open-label randomised controlled trial comparing ferric carboxymaltose with the standard of care in anaemic Malawian pregnant women: the REVAMP trial
Mwangi, MN; Mzembe, G; Moya, E; Braat, S; Harding, R; Robberstad, B; Simpson, J; Stones, W; Rogerson, S; Biselele, K; Chinkhumba, J; Larson, L; Ataide, R; Phiri, KS; Pasricha, SR
(2021), BMJ Open
Bispecific antibody therapy, its use and risks for infection: Bridging the knowledge gap
Longhitano, AP; Slavin, MA; Harrison, SJ; Teh, BW
(2021), Blood Rev.
Zanubrutinib for the treatment of relapsed or refractory mantle cell lymphoma
Tam, CS; Opat, S; Simpson, D; Cull, G; Munoz, J; Phillips, TJ; Kim, WS; Rule, S; Atwal, SK; Wei, R; Novotny, W; Huang, J; Wang, M; Trotman, J
(2021), Blood Adv., 2577-2585
Tisagenlecleucel immunogenicity in relapsed/refractory acute lymphoblastic leukemia and diffuse large B-cell lymphoma
Mueller, KT; Grupp, SA; Maude, SL; Levine, JE; Pulsipher, MA; Boyer, MW; August, KJ; Myers, GD; Tam, CS; Jaeger, U; Foley, SR; Borchmann, P; Schuster, SJ; Waller, EK; Awasthi, R; Potthoff, B; Warren, A; Waldron, ER; McBlane, F; Chassot-Agostinho, A; Laetsch, TW
(2021), Blood Adv., 4980-4991
Phase 1b study of the BET protein inhibitor RO6870810 with venetoclax and rituximab in patients with diffuse large B-cell lymphoma
Dickinson, M; Briones, J; Herrera, AF; Gonzalez-Barca, E; Ghosh, N; Cordoba, R; Rutherford, SC; Bournazou, E; Labriola-Tompkins, E; Franjkovic, I; Chesne, E; Brouwer-Visser, J; Lechner, K; Brennan, B; Nuesch, E; DeMario, M; Ruttinger, D; Kornacker, M; Hutchings, M
(2021), Blood Adv., 4762-4770
Outcomes of patients with CLL sequentially resistant to both BCL2 and BTK inhibition
Lew, TE; Lin, VS; Cliff, ER; Blombery, P; Thompson, ER; Handunnetti, SM; Westerman, DA; Kuss, BJ; Tam, CS; Huang, DCS; Seymour, JF; Roberts, AW; Anderson, MA
(2021), Blood Adv., 4054-4058
Clinical impact of NPM1-mutant molecular persistence after chemotherapy for acute myeloid leukemia
Tiong, IS; Dillon, R; Ivey, A; Kuzich, JA; Thiagarajah, N; Sharplin, KM; Kok, CH; Tedjaseputra, A; Rowland, JP; Grove, CS; Abro, E; Shortt, J; Hiwase, DK; Bajel, A; Potter, NE; Smith, ML; Hemmaway, CJ; Thomas, A; Gilkes, AF; Russell, NH; Wei, AH
(2021), Blood Adv., 5107-5111
KRd: the new KiD in the French myeloma induction class
Er, J; Harrison, SJ
(2021), Blood, 105-106
Investigation of product-derived lymphoma following infusion of piggyBac-modified CD19 chimeric antigen receptor T cells
Micklethwaite, KP; Gowrishankar, K; Gloss, BS; Li, ZD; Street, JA; Moezzi, L; Mach, MA; Sutrave, G; Clancy, LE; Bishop, DC; Louie, RHY; Cai, C; Foox, J; MacKay, M; Sedlazeck, FJ; Blombery, P; Mason, CE; Luciani, F; Gottlieb, DJ; Blyth, E
(2021), Blood, 1391-1405
Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias
Thijssen, R; Diepstraten, ST; Moujalled, D; Chew, E; Flensburg, C; Shi, MX; Dengler, MA; Litalien, V; MacRaild, S; Chen, M; Anstee, NS; Reljic, B; Gabriel, SS; Djajawi, TM; Riffkin, CD; Aubrey, BJ; Chang, C; Tai, L; Xu, Z; Morley, T; Pomilio, G; Bruedigam, C; Kallies, A; Stroud, DA; Bajel, A; Kluck, RM; Lane, SW; Schoumacher, M; Banquet, S; Majewski, IJ; Strasser, A; Roberts, AW; Huang, DCS; Brown, FC; Kelly, GL; Wei, AH
(2021), Blood, 2721-2735
How I treat chronic lymphocytic leukemia after venetoclax
Lew, TE; Tam, CS; Seymour, JF
(2021), Blood, 361-369
Efficacy of venetoclax plus rituximab for relapsed CLL: 5-year follow-up of continuous or limited-duration therapy
Ma, S; Seymour, JF; Brander, DM; Kipps, TJ; Choi, MY; Anderson, MA; Humphrey, K; Al Masud, A; Pesko, J; Nandam, R; Salem, AH; Chyla, B; Arzt, J; Jacobson, A; Kim, SY; Roberts, AW
(2021), Blood, 836-846
BCL2 and MCL1 inhibitors for hematologic malignancies
Roberts, AW; Wei, AH; Huang, DCS
(2021), Blood, 1120-1136
A phase 3, open-label, randomized study of asciminib, a STAMP inhibitor, vs bosutinib in CML after 2 or more prior TKIs
Rea, D; Mauro, MJ; Boquimpani, C; Minami, Y; Lomaia, E; Voloshin, S; Turkina, A; Kim, DW; Apperley, JF; Abdo, A; Fogliatto, LM; Kim, DDH; le Coutre, P; Saussele, S; Annunziata, M; Hughes, TP; Chaudhri, N; Sasaki, K; Chee, L; Garcia-Gutierrez, V; Cortes, JE; Aimone, P; Allepuz, A; Quenet, S; Bedoucha, V; Hochhaus, A
(2021), Blood, 2031-2041
A Wolf in Sheep's clothing: A case report series of oral manifestations of multiple myeloma
Beaumont, S; Koo, RM; Harrison, SJ
(2021), Aust. Dent. J., 324-331
DOI: 10.1111/adj.12808
Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines tor diagnosis, treatment and follow-up
Dreyling, M; Ghielmini, M; Rule, S; Salles, G; Ladetto, M; Tonino, SH; Herfarth, K; Seymour, JF; Jerkeman, M
(2021), Ann. Oncol., 298-308
A homozygous truncating variant in GDF9 in siblings with primary ovarian insufficiency
Verma, KP; Thompson, B; Wolfe, J; Price, S; Djukiadmodjo, F; Trainer, A
(2021), J. Assist. Reprod. Genet., 1539-1543
Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer
Matejcic, M; Shaban, HA; Quintana, MW; Schumacher, FR; Edlund, CK; Naghi, L; Pai, RK; Haile, RW; Levine, AJ; Buchanan, DD; Jenkins, MA; Figueiredo, JC; Rennert, G; Gruber, SB; Li, L; Casey, G; Conti, DV; Schmit, SL
(2021), Cancer Epidemiol. Biomarkers Prev., 895-903
Genetic testing in dementia-A medical genetics perspective
Huq, AJ; Sexton, A; Lacaze, P; Masters, CL; Storey, E; Velakoulis, D; James, PA; Winship, IM
(2021), Int. J. Geriatr. Psychiatr., 1158-1170
DOI: 10.1002/gps.5535
The Dose Makes the Poison
Brodtmann, A; Huq, A
(2021), Neurol.-Genet.
Germline and Tumor Sequencing as a Diagnostic Tool To Resolve Suspected Lynch Syndrome
Pope, BJ; Clendenning, M; Rosty, C; Mahmood, K; Georgeson, P; Joo, JE; Walker, R; Hutchinson, RA; Jayasekara, H; Joseland, S; Como, J; Preston, S; Spurdle, AB; Macrae, FA; Win, AK; Hopper, JL; Jenkins, MA; Winship, IM; Buchanan, DD
(2021), J. Mol. Diagn., 358-371
Evaluating the utility of tumour mutational signatures for identifying hereditary colorectal cancer and polyposis syndrome carriers
Georgeson, P; Pope, BJ; Rosty, C; Clendenning, M; Mahmood, K; Joo, JE; Walker, R; Hutchinson, RA; Preston, S; Como, J; Joseland, S; Win, AK; Macrae, FA; Hopper, JL; Mouradov, D; Gibbs, P; Sieber, OM; O'Sullivan, DE; Brenner, DR; Gallinger, S; Jenkins, MA; Winship, IM; Buchanan, DD
(2021), Gut, 2138-2149
DNA Methylation Signatures and the Contribution of Age-Associated Methylomic Drift to Carcinogenesis in Early-Onset Colorectal Cancer
Joo, JE; Clendenning, M; Wong, EM; Rosty, C; Mahmood, K; Georgeson, P; Winship, IM; Preston, SG; Win, AK; Dugue, PA; Jayasekara, H; English, D; Macrae, FA; Hopper, JL; Jenkins, MA; Milne, RL; Giles, GG; Southey, MC; Buchanan, DD
(2021), Cancers
Universal genetic testing of patients with newly diagnosed breast cancer - ready for prime time?
De Silva, DL; James, PA; Mann, GB; Lindeman, GJ
(2021), Med. J. Aust., 449
DOI: 10.5694/mja2.51317
Commentary: Pivoting during a pandemic: developing a new recruitment model for a randomised controlled trial in response to COVID-19
Milton, S; McIntosh, J; Boyd, L; Karnchanachari, N; Macrae, F; Emery, JD
(2021), Trials
Suicide in frontotemporal dementia and Huntington disease: analysis of family-reported pedigree data and implications for genetic healthcare for asymptomatic relatives
Sexton, A; West, K; Gill, G; Wiseman, A; Taylor, J; Purvis, R; Fahey, M; Storey, E; Walsh, M; James, P
(2021), Psychol. Health, 1397-1402
Communicating polygenic risk scores in the familial breast cancer clinic
Das Gupta, K; Gregory, G; Meiser, B; Kaur, R; Scheepers-Joynt, M; McInerny, S; Taylor, S; Barlow-Stewart, K; Antill, Y; Salmon, L; Smyth, C; McInerney-Leo, A; Young, MA; James, PA; Yanes, T
(2021), Patient Educ. Couns., 2512-2521
Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study
Nounu, A; Richmond, RC; Stewart, ID; Surendran, P; Wareham, NJ; Butterworth, A; Weinstein, SJ; Albanes, D; Baron, JA; Hopper, JL; Figueiredo, JC; Newcomb, PA; Lindor, NM; Casey, G; Platz, EA; Marchand, LL; Ulrich, CM; Li, CI; van Dujinhoven, FJB; Gsur, A; Campbell, PT; Moreno, V; Vodicka, P; Vodickova, L; Amitay, E; Alwers, E; Chang-Claude, J; Sakoda, LC; Slattery, ML; Schoen, RE; Gunter, MJ; Castellvi-Bel, S; Kim, HR; Kweon, SS; Chan, AT; Li, L; Zheng, W; Bishop, DT; Buchanan, DD; Giles, GG; Gruber, SB; Rennert, G; Stadler, ZK; Harrison, TA; Lin, Y; Keku, TO; Woods, MO; Schafmayer, C; Van Guelpen, B; Gallinger, S; Hampel, H; Berndt, SI; Pharoah, PDP; Lindblom, A; Wolk, A; Wu, AH; White, E; Peters, U; Drew, DA; Scherer, D; Bermejo, JL; Brenner, H; Hoffmeister, M; Williams, AC; Relton, CL
(2021), Nutrients
DOI: 10.3390/nu13114164
Genetic variants associated with inherited cardiovascular disorders among 13,131 asymptomatic older adults of European descent
Lacaze, P; Sebra, R; Riaz, M; Ingles, J; Tiller, J; Thompson, BA; James, PA; Fatkin, D; Semsarian, C; Reid, CM; Tonkin, AM; Winship, I; Schadt, E; McNeil, JJ
(2021), npj Genom. Med.
Population-based estimates of breast cancer risk for carriers of pathogenic variants identified by gene-panel testing
Southey, MC; Dowty, JG; Riaz, M; Steen, JA; Renault, AL; Tucker, K; Kirk, J; James, P; Winship, I; Pachter, N; Poplawski, N; Grist, S; Park, DJ; Pope, BJ; Mahmood, K; Hammet, F; Mahmoodi, M; Tsimiklis, H; Theys, D; Rewse, A; Willis, A; Morrow, A; Speechly, C; Harris, R; Sebra, R; Schadt, E; Lacaze, P; McNeil, JJ; Giles, GG; Milne, RL; Hopper, JL; Nguyen-Dumont, T
(2021), npj Breast Cancer