Clinical trials are a very important part of the research process. New treatments, medications and medical devices cannot be approved for use in Australia without going through clinical trials. Find out more about clinical trials.

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81 results found

Experimental treatment for people with herpes simplex virus type 2

This research study is to evaluate an experimental medication for people with Herpes Simplex Virus Type 2 (HSV-2)

Currently recruiting

Extended temozolomide chemotherapy period for glioblastoma

A clinical trial to determine if extending temozolomide treatment (chemotherapy) after radiation improves survival in patients with newly diagnosed glioblastoma.

Study in progress - not recruiting

Filgotinib for moderately to severely active Crohn’s disease

This trial aimed to evaluate the efficacy and safety of Filgotinib in the induction and maintenance of remission in people with moderately to severely active Crohn’s disease.

Study completed — 1

Geographic atrophy from age-related macular degeneration

The Golden trial is a study of a potential new treatment referred to as ISIS 696844 to determine its safety and effectiveness in slowing the progression of geographic atrophy (GA) caused by age-related macular degeneration (AMD).

Study in progress - not recruiting

Glucose control with next generation insulin pump system in adults with diabetes

A clinical trial to improve glucose control with a next generation insulin pump system in adults with diabetes and advanced kidney disease

Study completed — 2024

ICONIC-ASCEND

This study aims to assess efficacy and safety of JNJ-77242113 compared to placebo and ustekinumab in people with moderate to severe Plaque Psoriasis.

Currently recruiting

KBL697 for the treatment of ulcerative colitis

Study investigated Lactobacillus gasseri in patients with mild to moderate active ulcerative colitis.

Study completed — 1

KPL-716 to reduce pruritus in people with prurigo nodularis

A clinical trial to assess a new drug (KPL-716) for prurigo nodularis (PN).

Study in progress - not recruiting

Ligelizumab for chronic spontaneous urticaria

A clinical trial to assess a new drug called ligelizumab for the treatment of chronic spontaneous urticaria (CSU).

Study in progress - not recruiting

Mirikizumab for moderate to severely active Crohn’s disease

A clinical trial to assess the safety and effectiveness of a new drug, mirikizumab, for moderate to severely active Crohn’s disease.

Study in progress - not recruiting

Mirikizumabin for moderately to severely active ulcerative colitis

A clinical trial to assess the safety and effectiveness of a new drug, mirikizumab, in conventional-failed and biologic-failed patients with moderately to severely active ulcerative colitis (UC).

Study in progress - not recruiting

mRNA vaccine for preventing cytomegalovirus infection

A clinical trial seeking to develop an mRNA vaccine for preventing cytomegalovirus (CMV) infection.

Study in progress - not recruiting

Nemolizumab for the treatment of moderate to severe atopic dermatitis

A clinical trial to assess safety and effectiveness of a new drug for eczema called nemolizumab.

Study in progress - not recruiting

Neural mechanisms of ketamine antidepressant treatment

The NeuroKet study aims to understand how ketamine works as an antidepressant medication. To find out, we are looking at brain activity using Magnetic Resonance Imaging (MRI) scans.

Currently recruiting

New add-on therapy to infliximab for ulcerative colitis

A clinical trial to assess the effectiveness of a new add-on therapy (PF-06687234) to infliximab.

Study completed — 2021

New blood test to detect bowel cancer

Seeking adults diagnosed with bowel cancer who will be having surgery, chemotherapy or radiation therapy in the next 30 days for a study to assess the effectiveness of a new blood test to detect bowel cancer.

Study in progress - not recruiting

New blood test to diagnose and monitor autoimmune blistering skin conditions

A prospective study on serum antibodies against target antigens of bullous autoimmune diseases and genetic susceptibility.

Currently recruiting

New drug for basal cell carcinoma

A study to assess the safety and efficacy of ASN-002 combined with a hedgehog pathway inhibitor (vismodegib) in the treatment of multiple low-risk basal cell carcinomas in sporadic or basal cell naevus syndrome patients.

Study is ongoing

New drug for moderate to severe hidradenitis suppurativa

A clinical trial to assess the safety and effectiveness of a new drug for hidradenitis suppurativa.

Study in progress - not recruiting

New potential treatment for adult males with Tourette Syndrome

A study to evaluate the safety and efficacy of new drug in male patients aged 18 to 50 with Tourette Syndrome (TS).

Study in progress - not recruiting

New treatment for moderate-to-severe plaque psoriasis

Treatments that are highly selective in inhibiting the body's immune response have the potential to increase quality of life for people with plaque psoriasis.

Study in progress - not recruiting

New treatment for people with type 2 diabetes who want better glucose and weight control

We are inviting adults with type 2 diabetes to take part in this study which aims to evaluate a potential new treatment designed to reduce blood glucose levels and body weight in people with type 2 diabetes.

Study in progress - not recruiting

New treatment for young people with depression

SKY-D is investigating whether ketamine is an effective treatment for young people with depression.

Study completed

Novel blood collection device to help resource-poor countries with diagnostic testing

Seeking VIDS patients who are living with hepatitis B, hepatitis C or HIV to provide blood samples for the development of a new diagnostic test sampling and storage device for resource-poor countries.

Study in progress - not recruiting

Novel treatment for non-alcoholic fatty liver disease

A trial to test the effectiveness of a novel non-invasive treatment for fatty liver disease.

Study in progress - not recruiting

OPT-302 with ranibizumab for neovascular age-related macular degeneration

The ShORe trial aims to determine if the investigational medication OPT-302 will improve vision for people with wet age-related macular degeneration (AMD) when given in combination with ranibizumab, compared to ranibizumab alone.

Study in progress - not recruiting

Perampanel to control and prevent seizures in patients with brain tumours

A randomised controlled trial assessing the safety and effectiveness of perampanel, an anti-epileptic drug, in people with brain tumours.

Study in progress - not recruiting

Phase 3 study to assess efficacy, safety and tolerability of remibrutinib in adult patients with moderate to severe hidradenitis suppurativa (HS)

This study aims to understand how effective and safe remibrutinib is for people with hidradenitis suppurativa (HS), how remibrutinib affects their daily lives, and helps to improve their overall health and wellbeing.

Currently recruiting

Possible new drug for Crohn’s disease

We aimed to determine the safety and effectiveness of a new study medication, guselkumab, for people with Crohn's disease

Study in progress - not recruiting

Possible treatment for Parkinson’s disease

Cerevel Therapeutics has begun a study of an experimental drug called CVL-751 as a possible treatment for people with Parkinson’s disease. 

Currently recruiting